Portal de investigación
Polímeros Terapéuticos diseñados para cruzar la Barrera Hematoencefálica para el tratamiento de desordenes neurodegenerativos-Explorando la Ruta Intranasal.
Datos básicos
- Código Financiador:
- Año inicial:
- 2016
- Año final:
- 2019
Documentos
- No hay documentos
Participantes
Grupos de Investigación
Financiadores
Resultados del Proyecto
A POLYMER CONJUGATE NANOMEDICINE INHIBITS LPS-INDUCED MAPK ACTIVATION AND REDUCES ENDOTOXEMIA-MEDIATED KIDNEY INFLAMMATION
Gonzalez-Guerrero, C; (...); Ramos, A
Meeting Abstract. 2017
Anticancer Activity Driven by Drug Linker Modification in a Polyglutamic Acid-Based Combination-Drug Conjugate
Arroyo-Crespo, JJ; (...); Vicent, MJ
Article. 10.1002/adfm.201800931. 2018
Capturing "Extraordinary" Soft-Assembled Charge-Like Polypeptides as a Strategy for Nanocarrier Design
Duro-Castano, A; (...); Vicent, MJ
Article. 10.1002/adma.201702888. 2017
Combined polymer-curcumin conjugate and ependymal progenitor/stem cell treatment enhances spinal cord injury functional recovery
Requejo-Aguilar, R; (...); Moreno-Manzano, V
Article. 10.1016/j.biomaterials.2016.10.032. 2017
Covalently captured dynamic self-assembled star-shaped polyglutamates as drug delivery vehicles
Duro-Castano, A; (...); Vicent, M
Meeting Abstract. 2017
Characterization of triple-negative breast cancer preclinical models provides functional evidence of metastatic progression
Arroyo-Crespo JJ; (...); Vicent MJ
Article. 10.1002/ijc.32270. 2019
Design of personalised polymer based combination therapeutics for advanced stage breast cancer patients
Arminan, A; (...); Vicent, MJ
Meeting Abstract. 10.1158/1538-7445.AM2018-3726. 2018
Design of Poly-l-Glutamate-Based Complexes for pDNA Delivery
Nino-Pariente, A; (...); Vicent, MJ
Article. 10.1002/mabi.201700029. 2017
Design of Poly-l-Glutamate-Based Complexes for pDNA Delivery (vol 10, 1700029, 2017)
Nino-Pariente, A; (...); Vicent, MJ
Correction. 10.1002/mabi.201700245. 2017
Envisioning the future of polymer therapeutics for brain disorders
Rodriguez-Otormin, F; (...); Vicent, MJ
Review. 10.1002/wnan.1532. 2019
EU-OPENSCREEN: A Novel Collaborative Approach to Facilitate Chemical Biology
Brennecke, P; (...); Gribbon, P
Article. 10.1177/2472555218816276. 2019
Functionalized branched polymers: promising immunomodulatory tools for the treatment of cancer and immune disorders
Moura, LIF; (...); Florindo, HF
Review. 10.1039/c9mh00628a. 2019
Hemodynamic effects of HPMA copolymer based doxorubicin conjugate: A randomized controlled and comparative spectral study in conscious rats
Cheah, HY; (...); Japundzic-Zigon, N
Article. 10.1080/17435390.2017.1285071. 2017
HIF-1 alpha inhibition by diethylstilbestrol and its polyacetal conjugate in hypoxic prostate tumour cells: insights from NMR metabolomics
Arminan, A; (...); Duarte, IF
Article. 10.1080/1061186X.2017.1358728. 2017
High- throughput screening using a Drosophila model of Parkinson's disease
Lopez, FJ; (...); Paricio, N
Meeting Abstract. 2019
High-throughput screening of new drugs targeting lung CSCs
Labrador, HAA; (...); Camps, C
Meeting Abstract. 2018
In Vivo Imaging of MMP-13 Activity Using a Specific Polymer-FRET Peptide Conjugate Detects Early Osteoarthritis and Inhibitor Efficacy
Duro-Castano, A; (...); Nagase, H
Article. 10.1002/adfm.201802738. 2018
Integrin-targeted nano-sized polymeric systems for paclitaxel conjugation: a comparative study
Eldar-Boock, A; (...); Satchi-Fainaro, R
Article. 10.1080/1061186X.2017.1358727. 2017
Metabolomics facilitates the discrimination of the specific and-cancer effects of free and polymer conjugated doxorubicin in breast cancer models
Arminan, A; (...); Pineda-Lucena, A
Article. 10.1016/j.biomaterials.2018.02.015. 2018
Modulating angiogenesis with integrin-targeted nanomedicines
Duro-Castano, A; (...); Vicent, MJ
Review. 10.1016/j.addr.2017.05.008. 2017
Molecular platforms for targeted drug delivery
Maso K; (...); Pasut G
Review. 10.1016/bs.ircmb.2019.03.001. 2019
Near-Infrared Activatable Phthalocyanine Poly-L-Glutamic Acid Conjugate: Enhanced in Vivo Safety and Antitumor Efficacy toward an Effective Photodynamic Cancer Therapy
Cheah, HY; (...); Kiew, LV
Article. 10.1021/acs.molpharmaceut.8b00132. 2018
Near-infrared activatable phthalocyanine-poly-L-glutamic acid conjugate: increased cellular uptake and light-dark toxicity ratio toward an effective photodynamic cancer therapy
Kiew, LV; (...); Chung, LY
Article. 10.1016/j.nano.2017.02.002. 2017
pH-Responsive Polyacetal-Protein Conjugates Designed for Polymer Masked-Unmasked Protein Therapy (PUMPT)
Escalona, GR, Sanchis, J, Vicent, MJ
Article. 10.1002/mabi.201700302. 2018
Polyacetal-Based Combination Therapy for the Treatment of Prostate Cancer
Plyduang, T; (...); Vicent, MJ
Article. 10.1002/marc.201800265. 2018
Polymer therapeutics and stem cell therapies as a combinatorial approach for the treatment of chronic spinal cord injuries
Nebot, V; (...); Vicent, M
Meeting Abstract. 2017
Polymer Therapeutics: Biomarkers and New Approaches for Personalized Cancer Treatment
Atkinson SP, Andreu Z, Vicent MJ
Review. 10.3390/jpm8010006. 2018
Polyornithine-based polyplexes to boost effective gene silencing in CNS disorders.
Conejos-Sánchez I; (...); Vicent MJ
Article. 10.1039/c9nr06187h. 2020
Polypeptide-Based Conjugates as Therapeutics: Opportunities and Challenges
Zagorodko, O; (...); Vicent, MJ
Review. 10.1002/mabi.201600316. 2017
Polypeptide-based conjugates as versatile therapeutics as single agents or in combination therapy
Zagorodko, O; (...); Vicent, M
Meeting Abstract. 2019
Polypeptide-corticosteroid conjugates as a topical treatment approach to psoriasis
Dolz-Pérez I; (...); Vicent MJ
Article. 10.1016/j.jconrel.2019.12.016. 2020
Preclinical safety assessments of nano-sized constructs on cardiovascular system toxicity: A case for telemetry
Cheah, HY; (...); Chung, LY
Review. 10.1002/jat.3437. 2017
Professor Ruth Duncan: a pioneer in the field of polymer therapeutics.
Satchi-Fainaro, R, Vicent, MJ, Richardson, S
Editorial Material. 10.1080/1061186X.2017.1371722. 2017
Tumor microenvironment-targeted poly-L-glutamic acid-based combination conjugate for enhanced triple negative breast cancer treatment
Arroyo-Crespo JJ; (...); Vicent MJ
Article. 10.1016/j.biomaterials.2018.09.023. 2018
Use of polymer conjugates for the intraperoxisomal delivery of engineered human alanine: glyoxylate aminotransferase as a protein therapy for primary hyperoxaluria type I
Roncador, A; (...); Cellini, B
Article. 10.1016/j.nano.2016.12.011. 2017
Versatile star-shaped polypeptide conjugates with controlled self-assembly as therapeutics
Meeting Abstract. 2017