Regeneration of Injured Spinal cord by Electro pUlsed bio-hybrid imPlant

Datos básicos

Código Financiador:
Año inicial:
2021
Año final:
2024
PROY. INVEST. EUROPEA F.COMPETITIVA FIN. PUBLICA 508.185,00 €

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Grupos de Investigación

Financiadores

COMMISSION OF EUROPEAN COMMUNITIES

Resultados del Proyecto


A Hyaluronic Acid Demilune Scaffold and Polypyrrole-Coated Fibers Carrying Embedded Human Neural Precursor Cells and Curcumin for Surface Capping of Spinal Cord Injuries

Elkhenany, H; (...); Manzano, VM

Article. 10.3390/biomedicines9121928. 2021

  • Open Access.

A rationally designed self-immolative linker enhances the synergism between a polymer-rock inhibitor conjugate and neural progenitor cells in the treatment of spinal cord injury.

Giraldo E; (...); Moreno-Manzano V

Article. 10.1016/j.biomaterials.2021.121052. 2021


A Strategy for Magnetic and Electric Stimulation to Enhance Proliferation and Differentiation of NPCs Seeded over PLA Electrospun Membranes

Cuenca-Ortola, I; (...); Estelles, JM

Article. 10.3390/biomedicines10112736. 2022

  • Open Access.

Advanced Microdosimetric and Neurofunctionalized Multiphysics on Stem Cells Models Under Microsecond Pulse Stimulation

Fontana, S; (...); Liberti, M

Article. 10.1109/JERM.2024.3468024. 2024


Characterization of Mesenchymal and Neural Stem Cells Response to Bipolar Microsecond Electric Pulses Stimulation.

Innamorati G; (...); Consales C

Article. 10.3390/ijms26010147. 2024


Chondroitin sulfate proteoglycans prevent immune cell phenotypic conversion and inflammation resolution via TLR4 in rodent models of spinal cord injury.

Francos-Quijorna I; (...); Bradbury EJ

Article. 10.1038/s41467-022-30467-5. 2022

  • Open Access.

Engineered axon tracts within tubular biohybrid scaffolds

Doblado, LR; (...); Pradas, MM

Article. 10.1088/1741-2552/ac17d8. 2021

  • Open Access.

Extracellular vesicles from mesenchimal stem cells reduce neuroinflammation in hippocampus and restore cognitive function in hyperammonemic rats

Izquierdo-Altarejos, P; (...); Felipo, V

Meeting Abstract. 2022


Extracellular vesicles from mesenchymal stem cells improve neuroinflammation and neurotransmission in hippocampus and cognitive impairment in rats with mild liver damage and minimal hepatic encephalopathy.

Mincheva G; (...); Llansola M

Article. 10.1186/s13287-024-04076-6. 2024

  • Open Access.

Extracellular vesicles from mesenchymal stem cells reduce neuroinflammation in hippocampus and restore cognitive function in hyperammonemic rats.

Izquierdo-Altarejos P; (...); Felipo V

Article. 10.1186/s12974-022-02688-4. 2023

  • Open Access.

Extracellular Vesicles from Mesenchymal Stem Cells Reverse Neuroinflammation and Restore Motor Coordination in Hyperammonemic Rats.

Izquierdo-Altarejos P; (...); Felipo V

Article. 10.1007/s11481-024-10153-7. 2024


FM19G11-loaded nanoparticles modulate energetic status and production of reactive oxygen species in myoblasts from ALS mice

Malacarne, C; (...); Marcuzzo, S

Article. 10.1016/j.biopha.2024.116380. 2024

  • Open Access.

Human-Induced Neural and Mesenchymal Stem Cell Therapy Combined with a Curcumin Nanoconjugate as a Spinal Cord Injury Treatment

Bonilla, P; (...); Moreno-Manzano, V

Article. 10.3390/ijms22115966. 2021


NPC transplantation rescues sci-driven cAMP/EPAC2 alterations, leading to neuroprotection and microglial modulation

Martinez-Rojas, B; (...); Moreno-Manzano, V

Article. 10.1007/s00018-022-04494-w. 2022

  • Open Access.

Optogenetic Stimulation Array for Confocal Microscopy Fast Transient Monitoring

Monreal-Trigo, J; (...); Fillol, MA

Article. 10.1109/TBCAS.2022.3226558. 2022

  • Open Access.

Pathological and therapeutic effects of extracellular vesicles in neurological and neurodegenerative diseases.

Izquierdo-Altarejos P, Moreno-Manzano V, Felipo V

Article. 10.4103/1673-5374.375301. 2024

  • Open Access.

Peripheral Neuron Transplantation Overexpressing NaChBac as a Therapeutic Intervention for Spinal Cord Injury

Prakash, SHJ; (...); Moreno-Manzano, V

Meeting Abstract. 2023


Rehabilitation enhances epothilone-induced locomotor recovery after spinal cord injury

Griffin, JM; (...); Bradke, F

Article. 10.1093/braincomms/fcad005. 2022


Role of extracellular vesicles derived by mesenchymal stem cells in the neuroinflammation induced by intermittent ethanol treatment in adolescence

Mellado, S; (...); Pascual, M

Meeting Abstract. 2022


Sildenafil Citrate Enhances Renal Organogenesis Following Metanephroi Allotransplantation into Non-Immunosuppressed Hosts

Garcia-Dominguez, X; (...); Marco-Jimenez, F

Article. 10.3390/jcm11113068. 2022

  • Open Access.

Therapeutic role of mesenchymal stem cell-derived extracellular vesicles in neuroinflammation and cognitive dysfunctions induced by binge-like ethanol treatment in adolescent mice

Mellado, S; (...); Pascual, M

Article. 10.1111/cns.14326. 2023

  • Open Access.

Toll-like receptors 2 and 4 differentially regulate the self-renewal and differentiation of spinal cord neural precursor cells.

Sanchez-Petidier M, Guerri C, Moreno-Manzano V

Article. 10.1186/s13287-022-02798-z. 2022


Towards a new horizon in prostate cancer: PSMA-targeted Docetaxel-conjugated nanomedicines for intratumoral treatment in xenograft model

Gomez, AB; (...); Botella, P

Meeting Abstract. 2023


Transplantation of Human-Fetal-Spinal-Cord-Derived NPCs Primed with a Polyglutamate-Conjugated Rho/Rock Inhibitor in Acute Spinal Cord Injury.

Giraldo E; (...); Moreno Manzano V

Article. 10.3390/cells11203304. 2022

  • Open Access.

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