Portal de investigación
Generation of a human iPSC line from a patient with Leber congenital amaurosis caused by mutation in AIPL1
Autores de CIPF
Participantes ajenos a CIPF
- Corton, M
- Ayuso, C
Grupos de Investigación
Abstract
The human induced pluripotent stem cell (hiPSC) line, derived from dermal fibroblasts from Leber congenital amaurosis patient with homozygous mutation c.265 T > C, p.Cys89Arg in aryl hydrocarbon receptor-interacting protein-like 1 (AIPL1) was generated by Sendai virus reprogramming. The generated hiPSC line was free of Sendai virus genes, had stable karyotype, carried the homozygous mutation, was immunopositive to pluripotency markers and able to generate all three germ layers upon embryoid body formation.
Datos de la publicación
- ISSN/ISSNe:
- 1873-5061, 1876-7753
- Tipo:
- Editorial Material
- Páginas:
- 151-155
- PubMed:
- 30366342
Stem Cell Research ELSEVIER SCIENCE BV
Citas Recibidas en Web of Science: 3
Documentos
- No hay documentos
Filiaciones
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