Cerebellar cells derived from induced pluripotent stem cells in 3D culture generated from ARSACS patients as faithful disease model

Datos básicos

Código Financiador:
Año inicial:
2015
Año final:
2020
PROY. INVEST. INTERNACIONAL F.COMPETITIVA FIN. PRIVADA 69.468,57 €

Documentos

  • No hay documentos

Participantes

Grupos de Investigación

Financiadores

FONDATION DE L'ATAXIE CHARLEVOIX-SAGUENAY

Resultados del Proyecto


3D Retinal Cups from Human iPS Cells Display Differentiated Subtypes of Amacrine Cells and Immature Synaptic Contacts

Lukovic, D; (...); Erceg, S

Meeting Abstract. 2017


Activation of Neurogenesis in Multipotent Stem Cells CulturedIn Vitroand in the Spinal Cord Tissue After Severe Injury by Inhibition of Glycogen Synthase Kinase-3

Rodriguez-Jimenez, FJ; (...); Erceg, S

Article. 10.1007/s13311-020-00928-0. 2021


Assessment of Toxic Effects of Ochratoxin A in Human Embryonic Stem Cells

Erceg S; (...); Garcia-Esparza MÁ

Article. 10.3390/toxins11040217. 2019


Concise Review: Human Induced Pluripotent Stem Cell Models of Retinitis Pigmentosa

Castro, AA; (...); Erceg, S

Review. 10.1002/stem.2783. 2018


Connexin 50 Expression in Ependymal Stem Progenitor Cells after Spinal Cord Injury Activation

Rodriguez-Jimenez, FJ; (...); Moreno-Manzano, V

Article. 10.3390/ijms161125981. 2015


Connexin 50 modulates Sox2 expression in spinal-cord-derived ependymal stem/progenitor cells

Rodriguez-Jimenez, F; (...); Moreno-Manzano, V

Article. 10.1007/s00441-016-2421-y. 2016


Current developments in cell- and biomaterial-based approaches for stroke repair

Jendelova, P; (...); Sykova, E

Review. 10.1517/14712598.2016.1094457. 2016


Chronic hyperammonemia induces peripheral inflammation that leads to cognitive impairment in rats: Reversed by anti-TNF-alpha treatment

Balzano, T; (...); Felipo, V

Article. 10.1016/j.jhep.2019.01.008. 2020


Deciphering retinal diseases through the generation of three dimensional stem cell-derived organoids: Concise Review.

Artero Castro A; (...); Erceg S

Article. 10.1002/stem.3089. 2019


FM19G11 and Ependymal Progenitor/Stem Cell Combinatory Treatment Enhances Neuronal Preservation and Oligodendrogenesis after Severe Spinal Cord Injury

Alastrue-Agudo, A; (...); Moreno-Manzano, V

Article. 10.3390/ijms19010200. 2018


Gene-edited mouse models and human retinal organoids to study the function of CERKL, NR2E3 and ATXN3 genes in inherited retinal dystrophies

Marfany, G; (...); Gonzalez-Duarte, R

Meeting Abstract. 2019


Generation of a human iPSC line by mRNA reprogramming

Castro, AA; (...); Lukovic, D

Editorial Material. 10.1016/j.scr.2018.02.011. 2018


Generation of a human iPSC line by mRNA reprogramming (vol 28, pg 157, 218)

Castro, AA; (...); Lukovic, D

Correction. 10.1016/j.scr.2018.06.012. 2018


Generation of a human iPSC line from a patient with autosomal recessive spastic ataxia of Charlevoix-Saguenay (ARSACS) caused by mutation in SACSIN gene

MACHUCA, C.; (...); ERCEG, S.

Editorial Material. 10.1016/j.scr.2018.07.012. 2018

  • Open Access.

Generation of a human iPSC line from a patient with congenital glaucoma caused by mutation in CYP1B1 gene

Bolinches-Amoros, A; (...); Erceg, S

Editorial Material. 10.1016/j.scr.2018.01.004. 2018


Generation of a human iPSC line from a patient with Leber congenital amaurosis caused by mutation in AIPL1

Lukovic, D; (...); Erceg, S

Editorial Material. 10.1016/j.scr.2018.10.012. 2018


Generation of a human iPSC line froma patient with retinitis pigmentosa caused by mutation in PRPF8 gene

DUNJA LUKOVIC; (...); SLAVEN ERCEG VUKICEVIC

Editorial Material. 10.1016/j.scr.2017.03.007. 2017


Generation of an iPSC line from a retinitis pigmentosa patient carrying a homozygous mutation in CERKL and a healthy sibling

Bolinches-Amorós A; (...); Lukovic D

Editorial Material. 10.1016/j.scr.2019.101455. 2019


Generation of gene-corrected human induced pluripotent stem cell lines derived from retinitis pigmentosa patient with Ser331Cysfs*5 mutation in MERTK

Artero Castro A; (...); Erceg S

Editorial Material. 10.1016/j.scr.2018.11.003. 2019


Generation of human induced pluripotent stem cell (iPSC) line from an unaffected female carrier of mutation in SACSIN gene

Machuca, C; (...); Erceg, S

Editorial Material. 10.1016/j.scr.2018.10.016. 2018

  • Open Access.

Glaucoma as a Neurodegenerative Disease Caused by Intrinsic Vulnerability Factors.

Artero-Castro A; (...); Erceg S

Article. 10.1016/j.pneurobio.2020.101817. 2020


Highly Efficient Neural Conversion of Human Pluripotent Stem Cells in Adherent and Animal-Free Conditions

Lukovic, D; (...); Erceg, S

Article. 10.1002/sctm.16-0371. 2017


hiPSC Disease Modeling of Rare Hereditary Cerebellar Ataxias: Opportunities and Future Challenges

Lukovic, D; (...); Erceg, S

Article. 10.1177/1073858416672652. 2017


Human iPSC derived disease model of MERTK-associated retinitis pigmentosa

DUNJA LUKOVIC; (...); Bhattacharya, SS

Article. 10.1038/srep12910. 2015


IN VITRO MODULATION OF GSK3 PATHWAY IN MOUSE EPENDYMAL AND HUMAN PLURIPOTENT STEM CELLS AS A STRATEGY FOR DEVELOPMENT OF NEW CELL TREATMENTS FOR SPINAL CORD INJURY

Erceg, S; (...); Lukovic, D

Meeting Abstract. 2016


Methacrylate-endcapped caprolactone and FM19G11 provide a proper niche for spinal cord-derived neural cells

Valdes-Sanchez, T; (...); Moreno-Manzano, V

Article. 10.1002/term.1735. 2015


Modulation of astroglial niche by stem cells for spinal cord regeneration

Erceg, S

Meeting Abstract. 2017


Modulation of astrogliosis in combination of stem cell transplantation as a new strategy for the treatment of spinal cord injury

Erceg, S

Article. 2015


Neural Stem Cells Derived from Human-Induced Pluripotent Stem Cells and Their Use in Models of CNS Injury

Jendelova P, Sykova E, Erceg S

Article. 10.1007/978-3-319-93485-3_3. 2018


Organized Neurogenic-Niche-Like Pinwheel Structures Discovered in Spinal Cord Tissue-Derived Neurospheres

Rodriguez-Jimenez FJ; (...); Erceg S

Article. 10.3389/fcell.2019.00334. 2019


Retinal Organoids derived from hiPSCs of an AIPL1-LCA Patient Maintain Cytoarchitecture despite Reduced levels of Mutant AIPL1.

Lukovic D; (...); Erceg S

Article. 10.1038/s41598-020-62047-2. 2020


Short Review: Investigating ARSACS: models for understanding cerebellar degeneration

Artero Castro A; (...); Erceg S

Review. 10.1111/nan.12540. 2019


Stem Cell-Based Therapy in Transplantation and Immune-Mediated Diseases

Volarevic, V; (...); Stojkovic, M

Editorial Material. 10.1155/2017/7379136. 2017


Stem Cells and Labeling for Spinal Cord Injury

Gazdic, M; (...); Stojkovic, M

Review. 10.3390/ijms18010006. 2017


The identification of small molecules that stimulate retinal pigment epithelial cells: potential novel therapeutic options for treating retinopathies

Artero-Castro, A; (...); Erceg, S

Review. 10.1080/17460441.2019.1559148. 2019


Transcriptome-based molecular staging of human stem cell-derived retinal organoids uncovers accelerated photoreceptor differentiation by 9-cis retinal

Kaya, KD; (...); Swaroop, A

Article. 2019


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