Identification and modelling of molecular and cellular events of the inmune response associated to the appearence of minimal hepatic encephalopaty in cirrhotic patients

A multi-omic study for uncovering molecular mechanisms associated with hyperammonemia-induced cerebellar function impairment in rats

Tarazona, S; (...); Felipo, V

Article. 10.1007/s10565-020-09572-y. 2021

A Multiomics Study To Unravel the Effects of Developmental Exposure to Endosulfan in Rats: Molecular Explanation for Sex-Dependent Effects

Tarazona, S; (...); Llansola, M

Article. 10.1021/acschemneuro.9b00304. 2019

A New Score Unveils a High Prevalence of Mild Cognitive Impairment in Patients with Nonalcoholic Fatty Liver Disease

Gimenez-Garzo, C; (...); Montoliu, C

Article. 10.3390/jcm10132806. 2021

• 
• Documentos

Academic collaborative models fostering the translation of physiological in vitro systems from basic research into drug discovery

Silvestri, A; (...); Fecke, W

Review. 10.1016/j.drudis.2021.02.024. 2021

Bacteroides uniformis CECT 7771 Modulates the Brain Reward Response to Reduce Binge Eating and Anxiety-Like Behavior in Rat

Agusti, A; (...); Sanz, Y

Article. 10.1007/s12035-021-02462-2. 2021

• 
• Documentos

Blockade of nitric oxide signalling promotes resilience to the effects of social defeat stress on the conditioned rewarding properties of MDMA in mice

Garcia-Pardo, MP; (...); Aguilar, MA

Article. 10.1016/j.niox.2020.03.001. 2020

Blocking glycine receptors reduces neuroinflammation and restores neurotransmission in cerebellum through ADAM17-TNFR1-NF-?ß pathway.

Arenas YM; (...); Felipo V

Article. 10.1186/s12974-020-01941-y. 2020

Characterizing sensory thresholds and autonomic dysfunction in cirrhotic patients with minimal hepatic encephalopathy

Rega, D; (...); Montoliu, C

Meeting Abstract. 2021

Chronic hyperammonemia induces peripheral inflammation that leads to cognitive impairment in rats: Reversed by anti-TNF-alpha treatment

Balzano, T; (...); Felipo, V

Article. 10.1016/j.jhep.2019.01.008. 2020

Decreased Cognitive Performance Is Associated With Reduced Resting State Connectivity and Gray Matter Atrophy in Patients With Minimal Hepatic Encephalopathy

Garcia-Garcia, R; (...); Montoliu, C

Meeting Abstract. 10.14309/01.ajg.0000582196.79157.8c. 2019

Differential role of interleukin-1 beta in neuroinflammation-induced impairment of spatial and nonspatial memory in hyperammonemic rats

Taoro-González L; (...); Felipo V

Article. 10.1096/fj.201900230RR. 2019

Extracellular cGMP Reverses Altered Membrane Expression of AMPA Receptors in Hippocampus of Hyperammonemic Rats: Underlying Mechanisms

Taoro-Gonzalez L; (...); Felipo V

Article. 10.1007/s12035-018-1387-z. 2019

Extracellular Vesicles from Hyperammonemic Rats Induce Neuroinflammation and Motor Incoordination in Control Rats

Izquierdo-Altarejos, P; (...); Felipo, V

Article. 10.3390/cells9030572. 2020

• 
• Documentos

Hyperammonemia Alters the Function of AMPA and NMDA Receptors in Hippocampus: Extracellular cGMP Reverses Some of These Alterations

Sancho-Alonso, M; (...); Teruel-Marti, V

Article. 10.1007/s11064-022-03588-y. 2022

Hyperammonemia alters the mismatch negativity in the auditory evoked potential by altering functional connectivity and neurotransmission

Garcia-Garcia, R; (...); Felipo, V

Article. 10.1111/jnc.14941. 2020

Hyperammonemia Enhances GABAergic Neurotransmission in Hippocampus: Underlying Mechanisms and Modulation by Extracellular cGMP

Sancho-Alonso, M; (...); Felipo, V

Article. 10.1007/s12035-022-02803-9. 2022

Intracellular and extracelluar cyclic GMP in the brain and the hippocampus.

Taoro-González L; (...); Felipo V

Article. 10.1016/bs.vh.2021.11.006. 2022

Lymphocyte infiltration, glial activation and neuronal loss in cerebellum of patients with different stages of chronic liver disease

Balzano, T; (...); Felipo, V

Meeting Abstract. 2019

Metabolic syndrome is associated with poor response to rifaximin in minimal hepatic encephalopathy

Ballester, MP; (...); Montoliu, C

Article. 10.1038/s41598-022-06416-z. 2022

Motor and Cognitive Performance in Patients with Liver Cirrhosis with Minimal Hepatic Encephalopathy

San Martin-Valenzuela, C; (...); Montoliu, C

Article. 10.3390/jcm9072154. 2020

• 
• Documentos

Multi-omic analysis unveils biological pathways in peripheral immune system associated to minimal hepatic encephalopathy appearance in cirrhotic patients

Rubio, T; (...); Montoliu, C

Article. 10.1038/s41598-020-80941-7. 2021

• 
• Documentos

Multi-omic analysis unveils biological pathways in peripheral immune system associated to minimal hepatic encephalopathy appearance in cirrhotic patients

Rubio, T; (...); Montoliu, C

Meeting Abstract. 2021

Patients with Minimal Hepatic Encephalopathy Show Altered Thermal Sensitivity and Autonomic Function

Rega, D; (...); Montoliu, C

Article. 10.3390/jcm10020239. 2021

• 
• Documentos

Peripheral inflammation induces neuroinflammation that alters neurotransmission and cognitive and motor function in hepatic encephalopathy: Underlying mechanisms and therapeutic implications

Cabrera-Pastor A; (...); Felipo V

Review. 10.1111/apha.13270. 2019

Rifaximin improves neuroinflammation and neurotransmission in cerebellum and hippocampus of rats with mild liver damage

Ivaylova, G; (...); Felipo, V

Meeting Abstract. 2021

Rifaximin Prevents T-Lymphocytes and Macrophages Infiltration in Cerebellum and Restores Motor Incoordination in Rats with Mild Liver Damage

Balzano, T; (...); Felipo, V

Article. 10.3390/biomedicines9081002. 2021

Selective improvement by rifaximin of changes in the immunophenotype in patients who improve minimal hepatic encephalopathy

Mangas-Losada, A; (...); Felipo, V

Article. 10.1186/s12967-019-2046-5. 2019

Sleep study with actigraphy in patients affected by cirrhosis with and without minimal hepatic encephalopathy

Ipiens, C; (...); Montoliu, C

Meeting Abstract. 2021

Sustained hyperammonemia induces TNF-a in glial cells and Purkinje neurons by activating the TNFR1-NF-kappa B pathway

Ortiz, YMA; (...); Felipo, V

Meeting Abstract. 2021

Sustained hyperammonemia induces TNF-a IN Purkinje neurons by activating the TNFR1-NF-kappa B pathway

Balzano, T; (...); Felipo, V

Article. 10.1186/s12974-020-01746-z. 2020

Tadalafil Treatment Improves Inflammation, Cognitive Function, And Mismatch Negativity Of Patients With Low Urinary Tract Symptoms And Erectile Dysfunction

Urios, A; (...); Montoliu, C

Article. 10.1038/s41598-019-53136-y. 2019

The Dual Role of the GABA(A) Receptor in Peripheral Inflammation and Neuroinflammation: A Study in Hyperammonemic Rats

Malaguarnera, M; (...); Felipo, V

Article. 10.3390/ijms22136772. 2021

• 
• Documentos

The S1PR2-CCL2-BDNF-TrkB pathway mediates neuroinflammation and motor incoordination in hyperammonaemia

Arenas, YM; (...); Felipo, V

Article. 10.1111/nan.12799. 2022