El interactoma de membrana de las proteínas de la familia Bcl-2 como diana antitumoral

Datos básicos

Código Financiador:
Año inicial:
2021
Año final:
2024
PROY. INVEST. NACIONAL F.COMPETITIVA FIN. PUBLICA 260.150,00 €

Documentos

  • No hay documentos

Participantes

Grupos de Investigación

Financiadores

MINISTERIO DE CIENCIA, INNOVACION Y UNIVERSIDADES

Resultados del Proyecto


A renal clearable fluorogenic probe for in vivo ß-galactosidase activity detection during aging and senolysis

Rojas-Vázquez, S; (...); Martínez-Máñez, R

Article. 10.1038/s41467-024-44903-1. 2024

  • Open Access.

Combination of palbociclib with navitoclax based-therapies enhances in vivo antitumoral activity in triple-negative breast cancer.

Estepa-Fernández A; (...); Martínez-Máñez R

Article. 10.1016/j.phrs.2022.106628. 2023

  • Open Access.

Exploring the neuroprotective potential of antimicrobial peptides from Dinoponera quadriceps venom against pentylenetetrazole-induced seizures in vivo.

Paes LCF; (...); Martins AMC

Article. 10.1016/j.toxicon.2023.107538. 2024


High-Capacity Mesoporous Silica Nanocarriers of siRNA for Applications in Retinal Delivery.

Ultimo A; (...); Ruiz-Hernández E

Article. 10.3390/ijms24032753. 2023

  • Open Access.

Horseradish Peroxidase-Functionalized Gold Nanoconjugates for Breast Cancer Treatment Based on Enzyme Prodrug Therapy

Vivo-Llorca, G; (...); Martinez-Manez, R

Article. 10.2147/IJN.S323802. 2022


Identification of an ASC oligomerization inhibitor for the treatment of inflammatory diseases

Soriano-Teruel, PM; (...); Orzaez, M

Article. 10.1038/s41419-021-04420-1. 2021

  • Open Access.

Identification of NLRP3(PYD) Homo-Oligomerization Inhibitors with Anti-Inflammatory Activity

Ghafary, SM; (...); Hosseinkhani, S

Article. 10.3390/ijms23031651. 2022

  • Open Access.

Nanodevices for the Efficient Codelivery of CRISPR-Cas9 Editing Machinery and an Entrapped Cargo: A Proposal for Dual Anti-Inflammatory Therapy

Garcia-Fernandez, A; (...); Martinez-Manez, R

Article. 10.3390/pharmaceutics14071495. 2022

  • Open Access.

Pharmacological senolysis reduces doxorubicin-induced cardiotoxicity and improves cardiac function in mice

Lerida-Viso, A; (...); Martinez-Manez, R

Article. 10.1016/j.phrs.2022.106356. 2022


Phenotyping of cancer-associated somatic mutations in the BCL2 transmembrane domain

Leiva, D; (...); Orzáez, M

Article. 10.1038/s41389-024-00516-3. 2024


Rational design of a trypanocidal peptide derived from Dinoponera quadriceps venom.

Monteiro ML; (...); Martins AMC

Article. 10.1016/j.ejmech.2022.114624. 2022


Split-luciferase complementary assay of NLRP3 PYD-PYD interaction indicates inflammasome formation during inflammation.

Isazadeh M; (...); Hosseinkhani S

Article. 10.1016/j.ab.2021.114510. 2022


Targeted Delivery of the Pan-Inflammasome Inhibitor MM01 as an Alternative Approach to Acute Lung Injury Therapy.

García-Fernández A; (...); Orzáez M

Article. 10.1002/adhm.202301577. 2023

  • Open Access.

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