1. Inicio
  2. Publicaciones
  3. Eukaryotic Initiation Factor 5A2 localizes to actively translating ribosomes to promote cancer cell protrusions and invasive capacity.

Eukaryotic Initiation Factor 5A2 localizes to actively translating ribosomes to promote cancer cell protrusions and invasive capacity.

Fecha de publicación:

Autores de CIPF

Participantes ajenos a CIPF

  • Ferrando A

Grupos de Investigación

Abstract

Eukaryotic Initiation Factor 5A (eIF-5A), an essential translation factor, is post-translationally activated by the polyamine spermidine. Two human genes encode eIF-5A, being eIF5-A1 constitutively expressed whereas eIF5-A2 is frequently found overexpressed in human tumours. The contribution of both isoforms with regard to cellular proliferation and invasion in non-small cell lung cancer remains to be characterized.

Datos de la publicación

ISSN/ISSNe:
1478-811X, 1478-811X

Cell Communication and Signaling  BioMed Central

Tipo:
Article
Páginas:
54-54
PubMed:
36915194

Citas Recibidas en Web of Science: 9

Documentos

  • No hay documentos

Métricas

Filiaciones mostrar / ocultar

Keywords

  • Cell migration, Cytoskeleton organization, Eukaryotic translation initiation factor 5A2, Lung adenocarcinoma, TGFB1 signaling, Translating ribosomes

Campos de Estudio

Proyectos asociados

Personalized treatment against activated AP-1 pathway in lung and breast

Investigador Principal: ROSA M FARRÀS RIVERA

INSTITUTO DE SALUD CARLOS III . 2021

A sound proteome for a sound body: targeting proteolysis for proteome remodeling

Investigador Principal: ROSA M FARRÀS RIVERA

2021

Metabolic Reprogramming to Improve Immunotherapy in cancer

Investigador Principal: ROSA M FARRÀS RIVERA

CONSELLERIA DE EDUCACION . 2022

Compartir