A sound proteome for a sound body: targeting proteolysis for proteome remodeling

eIF5A is activated by virus infection or dsRNA and facilitates virus replication through modulation of interferon production

Seoane, R; (...); Rivas, C

Article. 10.3389/fcimb.2022.960138. 2022

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Eukaryotic Initiation Factor 5A2 localizes to actively translating ribosomes to promote cancer cell protrusions and invasive capacity.

Martínez-Férriz A; (...); Farràs R

Article. 10.1186/s12964-023-01076-6. 2023

In Vitro Effect of 9-Tetrahydrocannabinol and Cannabidiol on Cancer-Associated Fibroblasts Isolated from Lung Cancer.

Milián L; (...); Mata M

Article. 10.3390/ijms23126766. 2022

New roles for AP-1/JUNB in cell cycle control and tumorigenic cell invasion via regulation of cyclin E1 and TGF-ß2.

Pérez-Benavente B; (...); Farràs R

Article. 10.1186/s13059-022-02800-0. 2022

SUMOylation modulates eIF5A activities in both yeast and pancreatic ductal adenocarcinoma cells.

Seoane R; (...); Rivas C

Article. 10.1186/s11658-024-00533-5. 2024

Ubiquitin-mediated mechanisms of translational control.

Martínez-Férriz A; (...); Farràs R

Article. 10.1016/j.semcdb.2021.12.009. 2022