SUMOylation modulates eIF5A activities in both yeast and pancreatic ductal adenocarcinoma cells.

Fecha de publicación:

Autores de CIPF

Participantes ajenos a CIPF

  • Seoane R
  • Lama-Díaz T
  • Romero AM
  • El Motiam A
  • Vidal S
  • Bouzaher YH
  • Blanquer M
  • Tolosa RM
  • Castillo Mewa J
  • Rodríguez MS
  • García-Sastre A
  • Xirodimas D
  • Sutherland JD
  • Barrio R
  • Alepuz P
  • Blanco MG
  • Rivas C

Grupos de Investigación

Abstract

The eukaryotic translation initiation protein eIF5A is a highly conserved and essential factor that plays a critical role in different physiological and pathological processes including stress response and cancer. Different proteomic studies suggest that eIF5A may be a small ubiquitin-like modifier (SUMO) substrate, but whether eIF5A is indeed SUMOylated and how relevant is this modification for eIF5A activities are still unknown.

Datos de la publicación

ISSN/ISSNe:
1425-8153, 1689-1392

CELLULAR & MOLECULAR BIOLOGY LETTERS  BioMed Central Ltd.

Tipo:
Article
Páginas:
15-15
PubMed:
38229033

Citas Recibidas en Web of Science: 4

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Keywords

  • Pancreatic ductal adenocarcinoma, SUMO2, Stress granules, Stress response, eIF5A

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