Evaluation of cell therapy using genetically corrected RPE cells in small and large animals for the treatment of hereditary retinal dystrophies

Datos básicos

Código Financiador:
Año inicial:
2021
Año final:
2024
PROY. INVEST. NACIONAL F.COMPETITIVA FIN. PRIVADA 194.000,00 €

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Grupos de Investigación

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FUNDACION LA MARATO DE TV3

Resultados del Proyecto


Advantages of nanofibrous membranes for culturing of primary RPE cells compared to commercial scaffolds

Tichotova, L; (...); Ardan, T

Article. 10.1111/aos.15034. 2022


Alzheimer's disease and synapse Loss: What can we learn from induced pluripotent stem Cells?

Rodriguez-Jimenez FJ; (...); Erceg S

Article. 10.1016/j.jare.2023.01.006. 2023


Generation of three human iPSC lines from PLAN (PLA2G6-associated neurodegeneration) patients

Machuca, C; (...); Espinos, C

Article. 10.1016/j.scr.2021.102338. 2021

  • Open Access.

Mutant PRPF8 Causes Widespread Splicing Changes in Spliceosome Components in Retinitis Pigmentosa Patient iPSC-Derived RPE Cells

Arzalluz-Luque, A; (...); Lukovic, D

Article. 10.3389/fnins.2021.636969. 2021

  • Open Access.

Progress In Stem Cells Based Replacement Therapy for Retinal Pigment Epithelium: In Vitro Differentiation to In Vivo Delivery

Gupta, S; (...); Bharti, K

Review. 10.1093/stcltm/szad039. 2023

  • Open Access.

Retinal Pigment Epithelium Cell Development: Extrapolating Basic Biology to Stem Cell Research

Gupta, S; (...); Petrovski, G

Review. 10.3390/biomedicines11020310. 2023

  • Open Access.

Subretinal Implantation of Human Primary RPE Cells Cultured on Nanofibrous Membranes in Minipigs

Lytvynchuk, L; (...); Petrovski, G

Article. 10.3390/biomedicines10030669. 2022

  • Open Access.

Subretinal Implantation of RPE on a Carrier in Minipigs: Guidelines for Preoperative Preparations, Surgical Techniques, and Postoperative Care

Lytvynchuk, L; (...); Ardan, T

Article. 10.3791/63505. 2022


The activation of dormant ependymal cells following spinal cord injury.

Rodriguez-Jimenez FJ, Jendelova P, Erceg S

Article. 10.1186/s13287-023-03395-4. 2023

  • Open Access.

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