A deep transcriptome meta-analysis reveals sex differences in multiple sclerosis.

Autores de CIPF
Participantes ajenos a CIPF
- Soler-Sáez I
- Roig FJ
- Yanguas-Casás N
- Neva-Alejo A
- López-Cerdán A
- Stranger BE
Grupos de Investigación
Abstract
Multiple sclerosis (MS), a chronic auto-immune, inflammatory, and degenerative disease of the central nervous system, affects both males and females; however, females suffer from a higher risk of developing MS (2-3:1 ratio relative to males). The precise sex-based factors influencing risk of MS are currently unknown. Here, we explore the role of sex in MS to identify molecular mechanisms underlying observed MS sex differences that may guide novel therapeutic approaches tailored for males or females.
Datos de la publicación
- ISSN/ISSNe:
- 0969-9961, 1095-953X
- Tipo:
- Article
- Páginas:
- 106113-106113
- PubMed:
- 37023829
NEUROBIOLOGY OF DISEASE ACADEMIC PRESS INC ELSEVIER SCIENCE
Citas Recibidas en Web of Science: 15
Documentos
- No hay documentos
Filiaciones
Keywords
- Biomarkers, Functional profiling, Meta-analysis, Multiple sclerosis, Neurodegeneration, Sex-based differences
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