Nanoplataforma Polipeptídica Multimodal de Precisión para el Tratamiento y Monitorización de Tumores Metastásicos. Colab I-36, I-12, I-63, servicio citómica, uji y gva (Esther Roselló)

Datos básicos

Código Financiador:
Año inicial:
2022
Año final:
2025
PROY. INVEST. AUTONÓMICO F.COMPETITIVA FIN. PUBLICA 299.805,00 €

Documentos

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Participantes

Grupos de Investigación

Financiadores

CONSELLERIA DE EDUCACION

Resultados del Proyecto


A Comprehensive Transcriptional Signature in Pancreatic Ductal Adenocarcinoma Reveals New Insights into the Immune and Desmoplastic Microenvironments.

Pérez-Díez I; (...); García-García F

Article. 10.3390/cancers15112887. 2023

  • Open Access.

A deep transcriptome meta-analysis reveals sex differences in multiple sclerosis.

Català-Senent JF; (...); García-García F

Article. 10.1016/j.nbd.2023.106113. 2023

  • Open Access.

A Rapid, Convergent Approach to the Identification of Exosome Inhibitors in Breast Cancer Models.

Andreu Z; (...); Vicent MJ

Article. 10.7150/ntno.73606. 2023


A renal clearable fluorogenic probe for in vivo ß-galactosidase activity detection during aging and senolysis

Rojas-Vázquez, S; (...); Martínez-Máñez, R

Article. 10.1038/s41467-024-44903-1. 2024

  • Open Access.

Acclimation and Blood Sampling: Effects on Stress Markers in C57Bl/6J Mice.

Marin N; (...); Bisbal V

Article. 10.3390/ani13182816. 2023

  • Open Access.

An integrated approach to identifying sex-specific genes, transcription factors, and pathways relevant to Alzheimer's disease.

López-Cerdán A; (...); García-García F

Article. 10.1016/j.nbd.2024.106605. 2024

  • Open Access.

An Offset Patterned Cross-ß Structure in Assemblies of C 3 -Symmetric Peptide Amphiphiles.

Zagorodko O; (...); Vicent MJ

Article. 10.1002/chem.202303194. 2024

  • Open Access.

An SPM-Enriched Marine Oil Supplement Shifted Microglia Polarization toward M2, Ameliorating Retinal Degeneration in rd10 Mice.

Olivares-González L; (...); Rodrigo R

Article. 10.3390/antiox12010098. 2022

  • Open Access.

Combination of palbociclib with navitoclax based-therapies enhances in vivo antitumoral activity in triple-negative breast cancer.

Estepa-Fernández A; (...); Martínez-Máñez R

Article. 10.1016/j.phrs.2022.106628. 2023

  • Open Access.

Comparative profiling of whole-cell and exosome samples reveals protein signatures that stratify breast cancer subtypes.

Andreu Z; (...); Vicent MJ

Article. 10.1007/s00018-024-05403-z. 2024

  • Open Access.

Critical Design Strategies Supporting Optimized Drug Release from Polymer-Drug Conjugates.

Ðordevic S; (...); Vicent MJ

Article. 10.1002/smll.202303157. 2023

  • Open Access.

Characterisation of peptidylprolyl isomerase C as a novel player in the pathogenesis of chronic liver disease

Fuster-Martínez, I; (...); Blas-García, A

Meeting Abstract. 10.1016/s0168-8278(24)01737-9. 2024


Deciphering the sex bias in housekeeping gene expression in adipose tissue: a comprehensive meta-analysis of transcriptomic studies.

Guaita-Cespedes M; (...); Garcia-Garcia F

Article. 10.1186/s13293-023-00506-x. 2023

  • Open Access.

Evidence for cytotoxicity and mitochondrial dysfunction in human lung cells exposed to biomass burning aerosol constituents: Levoglucosan and 4-nitrocatechol

Khan, F; (...); Szmigielski, R

Article. 10.1016/j.envpol.2024.125173. 2024

  • Open Access.

Exploration of SUMO2/3 Expression Levels and Autophagy Process in Fragile X-Associated Tremor/Ataxia Syndrome: Addressing Study Limitations and Insights for Future Research.

Alvarez-Mora MI; (...); Rodriguez-Revenga L

Article. 10.3390/cells12192364. 2023

  • Open Access.

Exploring novel targets in hepatic stellate cell activation: interference with the mitochondrial function as part of the antifibrogenic effect of Rilpivirine

Benedicto, A; (...); Apostolova, N

Meeting Abstract. 10.1016/s0168-8278(24)00983-8. 2024


Exploring the neuroprotective potential of antimicrobial peptides from Dinoponera quadriceps venom against pentylenetetrazole-induced seizures in vivo.

Paes LCF; (...); Martins AMC

Article. 10.1016/j.toxicon.2023.107538. 2024


High-Capacity Mesoporous Silica Nanocarriers of siRNA for Applications in Retinal Delivery.

Ultimo A; (...); Ruiz-Hernández E

Article. 10.3390/ijms24032753. 2023

  • Open Access.

HLA-A, -B, -C and -DRB1 Association with Autism Spectrum Disorder Risk: A Sex-Related Analysis in Italian ASD Children and Their Siblings.

Guerini FR; (...); Clerici M

Article. 10.3390/ijms25189879. 2024


Integrated transcriptomic landscape of the effect of anti-steatotic treatments in high-fat diet mouse models of non-alcoholic fatty liver disease

Fuster-Martínez, I; (...); Blas-García, A

Article. 10.1002/path.6242. 2024

  • Open Access.

Landscape of sex differences in obesity and type 2 diabetes in subcutaneous adipose tissue: a systematic review and meta-analysis of transcriptomics studies.

Moldovan RA; (...); García-García F

Article. 10.1016/j.metabol.2025.156241. 2025


Lipidomic landscape of circulating extracellular vesicles isolated from adolescents exposed to ethanol intoxication: a sex difference study.

Perpiñá-Clérigues C; (...); Pascual M

Article. 10.1186/s13293-023-00502-1. 2023

  • Open Access.

MetaFun: unveiling sex-based differences in multiple transcriptomic studies through comprehensive functional meta-analysis.

Malmierca-Merlo P; (...); Garcia-Garcia F

Article. 10.1186/s13293-024-00640-0. 2024

  • Open Access.

Metagenomics Reveals Sex-Based Differences in Murine Fecal Microbiota Profiles Induced by Chronic Alcohol Consumption

Domínguez-Pino, M; (...); Pascual, M

Article. 10.3390/ijms252312534. 2024

  • Open Access.

MicroRNAs as potential biomarkers for childhood epilepsy

Domenech, S; (...); Espinós, C

Meeting Abstract. 2024


Minimal hepatic encephalopathy is associated to alterations in eye movements

Casanova-Ferrer, F; (...); Montoliu, C

Article. 10.1038/s41598-022-21230-3. 2022

  • Open Access.

Monitoring platelet function in marine mammals: Intracellular Ca 2+ mobilization as a biomarker of platelet activation.

Felipo-Benavent M; (...); Rubio-Guerri C

Article. 10.1016/j.dci.2023.105080. 2024

  • Open Access.

Morphology evolution of supramolecular aggregates from C3-symmetric peptide amphiphiles

Zagorodko, O, Melnyk, T, Vicent, MJ

Article. 10.1016/j.molliq.2024.125664. 2024


NMR-Based Mitochondria Metabolomic Profiling: A New Approach To Reveal Cancer-Associated Alterations.

Domingo-Ortí I; (...); Palomino-Schätzlein M

Article. 10.1021/acs.analchem.3c02432. 2023


Novel insight into the lipid network of plasma extracellular vesicles reveal sex-based differences in the lipidomic profile of alcohol use disorder patients.

Perpiñá-Clérigues C; (...); Pascual M

Article. 10.1186/s13293-024-00584-5. 2024

  • Open Access.

Phenotyping of cancer-associated somatic mutations in the BCL2 transmembrane domain

Leiva, D; (...); Orzáez, M

Article. 10.1038/s41389-024-00516-3. 2024


Physiological values of phagocytic capacity in marine mammals and alterations during pathological situations.

Felipo-Benavent M; (...); O'Connor JE

Article. 10.3389/fvets.2024.1389977. 2024

  • Open Access.

Poly-l-glutamic acid modification modulates the bio-nano interface of a therapeutic anti-IGF-1R antibody in prostate cancer.

Vicente-Ruiz S; (...); Vicent MJ

Article. 10.1016/j.biomaterials.2023.122280. 2023

  • Open Access.

Rapid degeneration of iPSC-derived motor neurons lacking Gdap1 engages a mitochondrial-sustained innate immune response.

León M; (...); Torres J

Article. 10.1038/s41420-023-01531-w. 2023

  • Open Access.

Rational design of a trypanocidal peptide derived from Dinoponera quadriceps venom.

Monteiro ML; (...); Martins AMC

Article. 10.1016/j.ejmech.2022.114624. 2022


Rational design of poly-L-glutamic acid-palbociclib conjugates for pediatric glioma treatment.

Melnyk T; (...); Vicent MJ

Article. 10.1016/j.jconrel.2023.01.079. 2023


SAM-UNETR: Clinically Significant Prostate Cancer Segmentation Using Transfer Learning From Large Model

Alzate-Grisales, JA; (...); de la Iglesia-Vayá, M

Article. 10.1109/ACCESS.2023.3326882. 2023

  • Open Access.

SARS-CoV-2-encoded small RNAs are able to repress the host expression of SERINC5 to facilitate viral replication.

Meseguer S; (...); Esplugues E

Article. 10.3389/fmicb.2023.1066493. 2023

  • Open Access.

Survival outcomes in ALK-positive NSCLC patients (p) treated 1st line brigatinib and impact of the ALK fusion variant

Provencio-Pulla, M; (...); Romero, A

Meeting Abstract. 10.1200/JCO.2023.41.16_suppl.e21015. 2023


Targeted Delivery of the Pan-Inflammasome Inhibitor MM01 as an Alternative Approach to Acute Lung Injury Therapy.

García-Fernández A; (...); Orzáez M

Article. 10.1002/adhm.202301577. 2023

  • Open Access.

The emerging role of mesenchymal stem cell-derived extracellular vesicles to ameliorate hippocampal NLRP3 inflammation induced by binge-like ethanol treatment in adolescence

Mellado, S; (...); Pascual, M

Article. 10.4103/NRR.NRR-D-23-01397. 2025

  • Open Access.

The impact of sex on gene expression in the brain of schizophrenic patients: a systematic review and meta-analysis of transcriptomic studies.

Carceller H; (...); García-García F

Article. 10.1186/s13293-024-00635-x. 2024

  • Open Access.

The role of microRNAs in understanding sex-based differences in Alzheimer's disease.

Llera-Oyola J; (...); García-García F

Article. 10.1186/s13293-024-00588-1. 2024

  • Open Access.

Transplantation of Human-Fetal-Spinal-Cord-Derived NPCs Primed with a Polyglutamate-Conjugated Rho/Rock Inhibitor in Acute Spinal Cord Injury.

Giraldo E; (...); Moreno Manzano V

Article. 10.3390/cells11203304. 2022

  • Open Access.

Unlocking the Mitochondria for Nanomedicine-based Treatments: Overcoming Biological Barriers, Improving Designs, and Selecting Verification Techniques.

Pegoraro C; (...); Vicent MJ

Article. 10.1016/j.addr.2024.115195. 2024

  • Open Access.

Unveiling Common Transcriptomic Features between Melanoma Brain Metastases and Neurodegenerative Diseases.

Soler-Sáez I; (...); García-García F

Article. 10.1016/j.jid.2024.09.005. 2024


Unveiling sex-based differences in Parkinson's disease: a comprehensive meta-analysis of transcriptomic studies.

López-Cerdán A; (...); García-García F

Article. 10.1186/s13293-022-00477-5. 2022

  • Open Access.

Vascular differences between IDH-wildtype glioblastoma and astrocytoma IDH-mutant grade 4 at imaging and transcriptomic levels.

Álvarez-Torres MDM; (...); García-Gómez JM

Article. 10.1002/nbm.5004. 2023

  • Open Access.

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