MetaFun: unveiling sex-based differences in multiple transcriptomic studies through comprehensive functional meta-analysis.

Fecha de publicación: 27/08/2024

Autores de CIPF

Francisco García García

Autor

Participantes ajenos a CIPF

Malmierca-Merlo P
Sánchez-Garcia R
Grillo-Risco R
Pérez-Díez I
Català-Senent JF
de la Iglesia-Vayá M
Hidalgo MR

Grupos de Investigación

Unidad de Bioinformática y Bioestadística

Jefe/a de Grupo

Francisco García García

Abstract

While sex-based differences in various health scenarios have been thoroughly acknowledged in the literature, we lack sufficient tools and methods that allow for an in-depth analysis of sex as a variable in biomedical research. To fill this knowledge gap, we created MetaFun as an easy-to-use web-based tool to meta-analyze multiple transcriptomic datasets with a sex-based perspective to gain major statistical power and biological soundness.

Datos de la publicación

ISSN/ISSNe:: 2042-6410, 2042-6410
Tipo:: Article
Páginas:: 66-66
DOI:: 10.1186/s13293-024-00640-0
PubMed:: 39192356

Documentos

No hay documentos

Métricas

Filiaciones

Malmierca-Merlo P:: Computational Biomedicine Laboratory, Principe Felipe Research Center (CIPF), Eduardo Primo Yúfera Street, 3, 46012, Valencia, Spain
Sánchez-Garcia R:: Computational Biomedicine Laboratory, Principe Felipe Research Center (CIPF), Eduardo Primo Yúfera Street, 3, 46012, Valencia, Spain
Grillo-Risco R:: Computational Biomedicine Laboratory, Principe Felipe Research Center (CIPF), Eduardo Primo Yúfera Street, 3, 46012, Valencia, Spain
Pérez-Díez I:: Computational Biomedicine Laboratory, Principe Felipe Research Center (CIPF), Eduardo Primo Yúfera Street, 3, 46012, Valencia, Spain

Biomedical Imaging Unit FISABIO-CIPF, Fundación Para El Fomento de La Investigación Sanitaria Y Biomédica de La Comunidad Valenciana, 46012, Valencia, Spain
Català-Senent JF:: Computational Biomedicine Laboratory, Principe Felipe Research Center (CIPF), Eduardo Primo Yúfera Street, 3, 46012, Valencia, Spain
de la Iglesia-Vayá M:: Biomedical Imaging Unit FISABIO-CIPF, Fundación Para El Fomento de La Investigación Sanitaria Y Biomédica de La Comunidad Valenciana, 46012, Valencia, Spain
Hidalgo MR:: Computational Biomedicine Laboratory, Principe Felipe Research Center (CIPF), Eduardo Primo Yúfera Street, 3, 46012, Valencia, Spain.

Department of Mathematics, Faculty of Mathematics, University of Valencia (UV), 46100, Burjassot-Valencia, Spain.
Garcia-Garcia F:: Computational Biomedicine Laboratory, Principe Felipe Research Center (CIPF), Eduardo Primo Yúfera Street, 3, 46012, Valencia, Spain.