Nuevo biomaterial bio-activo para la regeneración de lesiones medulares

Datos básicos

Código Financiador:
Año inicial:
2019
Año final:
2022
PROY. INVEST. NACIONAL F.COMPETITIVA FIN. PUBLICA 242.000,00 €

Documentos

  • No hay documentos

Participantes

Grupos de Investigación

Financiadores

MINISTERIO DE ECON. Y COMPET.

Resultados del Proyecto


A Hyaluronic Acid Demilune Scaffold and Polypyrrole-Coated Fibers Carrying Embedded Human Neural Precursor Cells and Curcumin for Surface Capping of Spinal Cord Injuries

Elkhenany, H; (...); Manzano, VM

Article. 10.3390/biomedicines9121928. 2021

  • Open Access.

A rationally designed self-immolative linker enhances the synergism between a polymer-rock inhibitor conjugate and neural progenitor cells in the treatment of spinal cord injury.

Giraldo E; (...); Moreno-Manzano V

Article. 10.1016/j.biomaterials.2021.121052. 2021


A synthetic mRNA cell reprogramming method using CYCLIN D1 promotes DNA repair generating improved genetically stable human induced pluripotent stem cells

Alvarez-Palomo, AB; (...); Edel, MJ

Article. 10.1002/stem.3358. 2021


Activation of Neurogenesis in Multipotent Stem Cells CulturedIn Vitroand in the Spinal Cord Tissue After Severe Injury by Inhibition of Glycogen Synthase Kinase-3

Rodriguez-Jimenez, FJ; (...); Erceg, S

Article. 10.1007/s13311-020-00928-0. 2021


Adult Neural Stem Cell Migration Is Impaired in a Mouse Model of Alzheimer's Disease

Esteve, D; (...); Lloret, A

Article. 10.1007/s12035-021-02620-6. 2022

  • Open Access.

Amino modified metal-organic frameworks as pH-responsive nanoplatforms for safe delivery of camptothecin

Cabrera-Garcia, A; (...); Botella, P

Article. 10.1016/j.jcis.2019.01.042. 2019


Author Correction: Mechanism and Consequences of The Impaired Hif-1a Response to Hypoxia in Human Proximal Tubular HK-2 Cells Exposed to High Glucose.

García-Pastor C; (...); Lucio-Cazaña FJ

Correction. 10.1038/s41598-020-65511-1. 2020


Biohybrids for spinal cord injury repair

Martínez-Ramos C; (...); Moreno-Manzano V

Article. 10.1002/term.2816. 2019


Chondroitin sulfate proteoglycans prevent immune cell phenotypic conversion and inflammation resolution via TLR4 in rodent models of spinal cord injury.

Francos-Quijorna I; (...); Bradbury EJ

Article. 10.1038/s41467-022-30467-5. 2022

  • Open Access.

Engineered axon tracts within tubular biohybrid scaffolds

Doblado, LR; (...); Pradas, MM

Article. 10.1088/1741-2552/ac17d8. 2021

  • Open Access.

Ependymal cells in the spinal cord as neuronal progenitors

Moreno-Manzano, V

Article. 10.1016/j.coph.2019.11.008. 2020


FM19G11-Loaded Gold Nanoparticles Enhance the Proliferation and Self-Renewal of Ependymal Stem Progenitor Cells Derived from ALS Mice

Marcuzzo S; (...); Bernasconi P

Article. 10.3390/cells8030279. 2019


Graphene oxide nanosheets versus carbon nanofibers: Enhancement of physical and biological properties of poly(3-hydroxybutyrate-co-3-hydroxyvalerate) films for biomedical applications.

Rivera-Briso AL; (...); Serrano-Aroca Á

Article. 10.1016/j.ijbiomac.2019.10.034. 2020


Human adipose-derived mesenchymal stem cells accelerate decellularized neobladder regeneration

Moreno-Manzano, V; (...); Vera-Donoso, CD

Article. 10.1093/rb/rbz049. 2020

  • Open Access.

Human-Induced Neural and Mesenchymal Stem Cell Therapy Combined with a Curcumin Nanoconjugate as a Spinal Cord Injury Treatment

Bonilla, P; (...); Moreno-Manzano, V

Article. 10.3390/ijms22115966. 2021


Increased basal antioxidant levels in RCAN1-deficient mice lowers oxidative injury after acute paraquat insult

Lloret, A; (...); Vina, J

Article. 10.1080/10715762.2020.1798002. 2020


Injectable Gel Form of a Decellularized Bladder Induces Adipose-Derived Stem Cell Differentiation into Smooth Muscle Cells In Vitro

Moreno-Manzano, V; (...); Serrano-Aroca, A

Article. 10.3390/ijms21228608. 2020


Isolation and phenotyping of potential stem cells from the umbilical cord of the bottlenose dolphin(Tursiops truncatus)

Mancia, A; (...); Moreno-Manzano, V

Article. 10.1387/ijdb.190042am. 2019


Mechanism and Consequences of The Impaired Hif-1 alpha Response to Hypoxia in Human Proximal Tubular HK-2 Cells Exposed to High Glucose

Garcia-Pastor, C; (...); Lucio-Cazana, FJ

Article. 10.1038/s41598-019-52310-6. 2019


Optogenetic Modulation of Neural Progenitor Cells Improves Neuroregenerative Potential

Giraldo, E; (...); Moreno-Manzano, V

Article. 10.3390/ijms22010365. 2021


Organized Neurogenic-Niche-Like Pinwheel Structures Discovered in Spinal Cord Tissue-Derived Neurospheres

Rodriguez-Jimenez FJ; (...); Erceg S

Article. 10.3389/fcell.2019.00334. 2019


Preclinical antitumor efficacy of senescence-inducing chemotherapy combined with a nanoSenolytic.

Galiana I; (...); Orzáez M

Article. 10.1016/j.jconrel.2020.04.045. 2020

  • Open Access.

PSMA-Targeted Mesoporous Silica Nanoparticles for Selective Intracellular Delivery of Docetaxel in Prostate Cancer Cells

Rivero-Buceta, E; (...); Botella, P

Article. 10.1021/acsomega.8b02909. 2019


Sequential pore wall functionalization in covalent organic frameworks and application to stable camptothecin delivery systems

Oliveira, AD; (...); Botella, P

Article. 10.1016/j.msec.2020.111263. 2020


Serum Levels of Clusterin, PKR, and RAGE Correlate with Amyloid Burden in Alzheimer's Disease

Monllor, P; (...); Vina, J

Article. 10.3233/JAD-201443. 2021


Sildenafil Citrate Enhances Renal Organogenesis Following Metanephroi Allotransplantation into Non-Immunosuppressed Hosts

Garcia-Dominguez, X; (...); Marco-Jimenez, F

Article. 10.3390/jcm11113068. 2022

  • Open Access.

tappAS: a comprehensive computational framework for the analysis of the functional impact of differential splicing

de la Fuente, L; (...); Conesa, A

Article. 10.1186/s13059-020-02028-w. 2020

  • Open Access.

Targeted-lung delivery of dexamethasone using gated mesoporous silica nanoparticles. A new therapeutic approach for acute lung injury treatment.

García-Fernández A; (...); Martínez-Máñez R

Article. 10.1016/j.jconrel.2021.07.010. 2021


Toll-like receptors 2 and 4 differentially regulate the self-renewal and differentiation of spinal cord neural precursor cells.

Sanchez-Petidier M, Guerri C, Moreno-Manzano V

Article. 10.1186/s13287-022-02798-z. 2022


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