Validación farmacológica in vivo de nanofármacos inhibidores de ROCK2 en cáncer de mama metastásico y lesión medular

Datos básicos

Código Financiador:
Año inicial:
2019
Año final:
2020
PROY. INVEST. AUTONÓMICO F.COMPETITIVA FIN. PUBLICA 144.187,00 €

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Participantes

Grupos de Investigación

Financiadores

AGENCIA VALENCIANA DE INNOVACIÓN

Resultados del Proyecto


Activation of Neurogenesis in Multipotent Stem Cells CulturedIn Vitroand in the Spinal Cord Tissue After Severe Injury by Inhibition of Glycogen Synthase Kinase-3

Rodriguez-Jimenez, FJ; (...); Erceg, S

Article. 10.1007/s13311-020-00928-0. 2021


Amino modified metal-organic frameworks as pH-responsive nanoplatforms for safe delivery of camptothecin

Cabrera-Garcia, A; (...); Botella, P

Article. 10.1016/j.jcis.2019.01.042. 2019


Author Correction: Mechanism and Consequences of The Impaired Hif-1a Response to Hypoxia in Human Proximal Tubular HK-2 Cells Exposed to High Glucose.

García-Pastor C; (...); Lucio-Cazaña FJ

Correction. 10.1038/s41598-020-65511-1. 2020


Biohybrids for spinal cord injury repair

Martínez-Ramos C; (...); Moreno-Manzano V

Article. 10.1002/term.2816. 2019


Characterization of triple-negative breast cancer preclinical models provides functional evidence of metastatic progression

Arroyo-Crespo JJ; (...); Vicent MJ

Article. 10.1002/ijc.32270. 2019


Effective Nephroprotection Against Acute Kidney Injury with a Star-Shaped Polyglutamate-Curcuminoid Conjugate

Cordoba-David, G; (...); Ramos, AM

Article. 10.1038/s41598-020-58974-9. 2020


Envisioning the future of polymer therapeutics for brain disorders

Rodriguez-Otormin, F; (...); Vicent, MJ

Review. 10.1002/wnan.1532. 2019


Ependymal cells in the spinal cord as neuronal progenitors

Moreno-Manzano, V

Article. 10.1016/j.coph.2019.11.008. 2020


EU-OPENSCREEN: A Novel Collaborative Approach to Facilitate Chemical Biology

Brennecke, P; (...); Gribbon, P

Article. 10.1177/2472555218816276. 2019


FM19G11-Loaded Gold Nanoparticles Enhance the Proliferation and Self-Renewal of Ependymal Stem Progenitor Cells Derived from ALS Mice

Marcuzzo S; (...); Bernasconi P

Article. 10.3390/cells8030279. 2019


Functionalized branched polymers: promising immunomodulatory tools for the treatment of cancer and immune disorders

Moura, LIF; (...); Florindo, HF

Review. 10.1039/c9mh00628a. 2019


Graphene oxide nanosheets versus carbon nanofibers: Enhancement of physical and biological properties of poly(3-hydroxybutyrate-co-3-hydroxyvalerate) films for biomedical applications.

Rivera-Briso AL; (...); Serrano-Aroca Á

Article. 10.1016/j.ijbiomac.2019.10.034. 2020


High- throughput screening using a Drosophila model of Parkinson's disease

Lopez, FJ; (...); Paricio, N

Meeting Abstract. 2019


Human adipose-derived mesenchymal stem cells accelerate decellularized neobladder regeneration

Moreno-Manzano, V; (...); Vera-Donoso, CD

Article. 10.1093/rb/rbz049. 2020

  • Open Access.

Increased basal antioxidant levels in RCAN1-deficient mice lowers oxidative injury after acute paraquat insult

Lloret, A; (...); Vina, J

Article. 10.1080/10715762.2020.1798002. 2020


Injectable Gel Form of a Decellularized Bladder Induces Adipose-Derived Stem Cell Differentiation into Smooth Muscle Cells In Vitro

Moreno-Manzano, V; (...); Serrano-Aroca, A

Article. 10.3390/ijms21228608. 2020


Isolation and phenotyping of potential stem cells from the umbilical cord of the bottlenose dolphin(Tursiops truncatus)

Mancia, A; (...); Moreno-Manzano, V

Article. 10.1387/ijdb.190042am. 2019


Mechanism and Consequences of The Impaired Hif-1 alpha Response to Hypoxia in Human Proximal Tubular HK-2 Cells Exposed to High Glucose

Garcia-Pastor, C; (...); Lucio-Cazana, FJ

Article. 10.1038/s41598-019-52310-6. 2019


Molecular platforms for targeted drug delivery

Maso K; (...); Pasut G

Review. 10.1016/bs.ircmb.2019.03.001. 2019


Nanomedicine for the Treatment of Advanced Prostate Cancer

Vicente-Ruiz, S; (...); Vicent, MJ

Review. 10.1002/adtp.202000136. 2021


Organized Neurogenic-Niche-Like Pinwheel Structures Discovered in Spinal Cord Tissue-Derived Neurospheres

Rodriguez-Jimenez FJ; (...); Erceg S

Article. 10.3389/fcell.2019.00334. 2019


Polyornithine-based polyplexes to boost effective gene silencing in CNS disorders.

Conejos-Sánchez I; (...); Vicent MJ

Article. 10.1039/c9nr06187h. 2020

  • Open Access.

Polypeptide-based conjugates as versatile therapeutics as single agents or in combination therapy

Zagorodko, O; (...); Vicent, M

Meeting Abstract. 2019


Polypeptide-corticosteroid conjugates as a topical treatment approach to psoriasis

Dolz-Pérez I; (...); Vicent MJ

Article. 10.1016/j.jconrel.2019.12.016. 2020


PSMA-Targeted Mesoporous Silica Nanoparticles for Selective Intracellular Delivery of Docetaxel in Prostate Cancer Cells

Rivero-Buceta, E; (...); Botella, P

Article. 10.1021/acsomega.8b02909. 2019


Sequential pore wall functionalization in covalent organic frameworks and application to stable camptothecin delivery systems

Oliveira, AD; (...); Botella, P

Article. 10.1016/j.msec.2020.111263. 2020


tappAS: a comprehensive computational framework for the analysis of the functional impact of differential splicing

de la Fuente, L; (...); Conesa, A

Article. 10.1186/s13059-020-02028-w. 2020

  • Open Access.

Targeting Pro-Tumoral Macrophages in Early Primary and Metastatic Breast Tumors with the CD206-Binding mUNO Peptide

Lepland, A; (...); Scodeller, P

Article. 10.1021/acs.molpharmaceut.0c00226. 2020


The generation of stabilized supramolecular nanorods from star-shaped polyglutamates

Zagorodko, O, Nebot, VJ, Vicent, MJ

Article. 10.1039/c9py01442j. 2020

  • Open Access.

Therapeutic potential of polypeptide-based conjugates: Rational design and analytical tools that can boost clinical translation.

Melnyk T; (...); Vicent MJ

Article. 10.1016/j.addr.2020.10.007. 2020


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