MEMBDEATH: Muerte celular y membranas: un nuevo nicho en la lucha contra el cáncer. Colab con la UV, no recibimos financiación

Datos básicos

Código Financiador:
Año inicial:
2019
Año final:
2022
PROY. INVEST. AUTONÓMICO F.COMPETITIVA FIN. PUBLICA

Documentos

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Grupos de Investigación

Financiadores

CONSELLERIA DE EDUCACION

Resultados del Proyecto


A NIR light-triggered drug delivery system using core-shell gold nanostars-mesoporous silica nanoparticles based on multiphoton absorption photo-dissociation of 2-nitrobenzyl PEG

Hernández-Montoto A; (...); Sancenón F

Article. 10.1039/c9cc04260a. 2019


BOK-MCL1 transmembrane interactions: a challenging target for cancer therapy

Sancho, M, Orzaez, M

Editorial Material. 10.1080/23723556.2020.1859918. 2021

  • Open Access.

Combination of palbociclib with navitoclax based-therapies enhances in vivo antitumoral activity in triple-negative breast cancer.

Estepa-Fernández A; (...); Martínez-Máñez R

Article. 10.1016/j.phrs.2022.106628. 2023

  • Open Access.

Dinoponera quadriceps venom as a source of active agents against Staphylococcus aureus

Rocha, LQ; (...); Martins, AMC

Article. 10.1016/j.toxicon.2020.11.003. 2021


EU-OPENSCREEN: A Novel Collaborative Approach to Facilitate Chemical Biology

Brennecke, P; (...); Gribbon, P

Article. 10.1177/2472555218816276. 2019


Gene-Directed Enzyme Prodrug Therapy by Dendrimer-Like Mesoporous Silica Nanoparticles against Tumor Cells

Candela-Noguera, V; (...); Martinez-Manez, R

Article. 10.3390/nano11051298. 2021


Horseradish Peroxidase-Functionalized Gold Nanoconjugates for Breast Cancer Treatment Based on Enzyme Prodrug Therapy

Vivo-Llorca, G; (...); Martinez-Manez, R

Article. 10.2147/IJN.S323802. 2022


Identification of an ASC oligomerization inhibitor for the treatment of inflammatory diseases

Soriano-Teruel, PM; (...); Orzaez, M

Article. 10.1038/s41419-021-04420-1. 2021

  • Open Access.

Identification of NLRP3(PYD) Homo-Oligomerization Inhibitors with Anti-Inflammatory Activity

Ghafary, SM; (...); Hosseinkhani, S

Article. 10.3390/ijms23031651. 2022

  • Open Access.

Janus Gold Nanostars-Mesoporous Silica Nanoparticles for NIR-Light-Triggered Drug Delivery

Hernández Montoto A; (...); Sancenón F

Article. 10.1002/chem.201900750. 2019


Mcl-1 and Bok transmembrane domains: Unexpected players in the modulation of apoptosis.

Lucendo E; (...); Orzáez M

Article. 10.1073/pnas.2008885117. 2020

  • Open Access.

MUC1 Aptamer-Capped Mesoporous Silica Nanoparticles for Navitoclax Resistance Overcoming in Triple-Negative Breast Cancer

Vivo-Llorca, G; (...); Martinez-Manez, R

Article. 10.1002/chem.202001579. 2020


Nanodevices for the Efficient Codelivery of CRISPR-Cas9 Editing Machinery and an Entrapped Cargo: A Proposal for Dual Anti-Inflammatory Therapy

Garcia-Fernandez, A; (...); Martinez-Manez, R

Article. 10.3390/pharmaceutics14071495. 2022

  • Open Access.

Pharmacological senolysis reduces doxorubicin-induced cardiotoxicity and improves cardiac function in mice

Lerida-Viso, A; (...); Martinez-Manez, R

Article. 10.1016/j.phrs.2022.106356. 2022


Preclinical antitumor efficacy of senescence-inducing chemotherapy combined with a nanoSenolytic.

Galiana I; (...); Orzáez M

Article. 10.1016/j.jconrel.2020.04.045. 2020

  • Open Access.

Rational design of a trypanocidal peptide derived from Dinoponera quadriceps venom.

Monteiro ML; (...); Martins AMC

Article. 10.1016/j.ejmech.2022.114624. 2022


Real-Time In Vivo Detection of Cellular Senescence through the Controlled Release of the NIR Fluorescent Dye Nile Blue

Lozano-Torres, B; (...); Martinez-Manez, R

Article. 10.1002/anie.202004142. 2020

  • Open Access.

Senolysis Reduces Senescence in Veins and Cancer Cell Migration

Estepa-Fernandez, A; (...); Martinez-Manez, R

Article. 10.1002/adtp.202100149. 2021


Split-luciferase complementary assay of NLRP3 PYD-PYD interaction indicates inflammasome formation during inflammation.

Isazadeh M; (...); Hosseinkhani S

Article. 10.1016/j.ab.2021.114510. 2022


Targeted-lung delivery of dexamethasone using gated mesoporous silica nanoparticles. A new therapeutic approach for acute lung injury treatment.

García-Fernández A; (...); Martínez-Máñez R

Article. 10.1016/j.jconrel.2021.07.010. 2021


The chemistry of senescence

Lozono-Torres, B; (...); Sancenon, F

Review. 10.1038/s41570-019-0108-0. 2019


The past, present, and future of breast cancer models for nanomedicine development

Boix-Montesinos, P; (...); Vicent, MJ

Review. 10.1016/j.addr.2021.03.018. 2021


Understanding MCL1: from cellular function and regulation to pharmacological inhibition

Sancho, M; (...); Orzaez, M

Review. 10.1111/febs.16136. 2022


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