A NIR light-triggered drug delivery system using core-shell gold nanostars-mesoporous silica nanoparticles based on multiphoton absorption photo-dissociation of 2-nitrobenzyl PEG

Autores de CIPF

• 

  Maria Mar Orzáez Calatayud

  Autor

• María Dolores Marcos Martínez

  Autor

• Ramón Martínez Mañez

  Autor

• Félix Sancenón Galarza

  Autor

Participantes ajenos a CIPF

• Hernández-Montoto A
• Gorbe M
• Llopis-Lorente A
• Terrés JM
• Montes R
• Cao-Milán R
• Díaz de Greñu B
• Alfonso M

Grupos de Investigación

• Laboratorio de Terapias Dirigidas en Cáncer e Inflamación

  

  Jefe/a de Grupo

  Maria Mar Orzáez Calatayud

Abstract

Gold nanostars coated with a mesoporous silica shell and functionalized with poly(ethylene glycol) containing photolabile 2-nitrobenzyl moieties are able to release doxorubicin after NIR light irradiation at low power irradiance via a multiphoton absorption photo-dissociation process.