Descifrando y modulando el interactoma transmembrana de las proteínas Bcl-2 como diana antitumoral

Datos básicos

Código Financiador:
Año inicial:
2018
Año final:
2021
PROY. INVEST. NACIONAL F.COMPETITIVA FIN. PUBLICA 181.500,00 €

Documentos

  • No hay documentos

Participantes

Grupos de Investigación

Financiadores

MINISTERIO DE ECON. Y COMPET.

Resultados del Proyecto


A NIR light-triggered drug delivery system using core-shell gold nanostars-mesoporous silica nanoparticles based on multiphoton absorption photo-dissociation of 2-nitrobenzyl PEG

Hernández-Montoto A; (...); Sancenón F

Article. 10.1039/c9cc04260a. 2019


BOK-MCL1 transmembrane interactions: a challenging target for cancer therapy

Sancho, M, Orzaez, M

Editorial Material. 10.1080/23723556.2020.1859918. 2021

  • Open Access.

Cytochrome c speeds up caspase cascade activation by blocking 14-3-3 epsilon-dependent Apaf-1 inhibition

Elena-Real, CA; (...); Diaz-Moreno, I

Article. 10.1038/s41419-018-0408-1. 2018


Dinoponera quadriceps venom as a source of active agents against Staphylococcus aureus

Rocha, LQ; (...); Martins, AMC

Article. 10.1016/j.toxicon.2020.11.003. 2021


EU-OPENSCREEN: A Novel Collaborative Approach to Facilitate Chemical Biology

Brennecke, P; (...); Gribbon, P

Article. 10.1177/2472555218816276. 2019


Gene-Directed Enzyme Prodrug Therapy by Dendrimer-Like Mesoporous Silica Nanoparticles against Tumor Cells

Candela-Noguera, V; (...); Martinez-Manez, R

Article. 10.3390/nano11051298. 2021


Gold Nanostars Coated with Mesoporous Silica Are Effective and Nontoxic Photothermal Agents Capable of Gate Keeping and Laser Induced Drug Release

Hernández Montoto A; (...); Martínez-Máñez R

Article. 10.1021/acsami.8b08395. 2018


Hybrid Mesoporous Nanocarriers Act by Processing Logic Tasks: Toward the Design of Nanobots Capable of Reading Information from the Environment

Llopis-Lorente, A; (...); Martinez-Manez, R

Article. 10.1021/acsami.8b05920. 2018


Janus Gold Nanostars-Mesoporous Silica Nanoparticles for NIR-Light-Triggered Drug Delivery

Hernández Montoto A; (...); Sancenón F

Article. 10.1002/chem.201900750. 2019


Mcl-1 and Bok transmembrane domains: Unexpected players in the modulation of apoptosis.

Lucendo E; (...); Orzáez M

Article. 10.1073/pnas.2008885117. 2020

  • Open Access.

MUC1 Aptamer-Capped Mesoporous Silica Nanoparticles for Navitoclax Resistance Overcoming in Triple-Negative Breast Cancer

Vivo-Llorca, G; (...); Martinez-Manez, R

Article. 10.1002/chem.202001579. 2020


New genes involved in diseases with neurodegeneration with brain iron accumulation (NBIA)

Martinez-Rubio, D; (...); Espinos, C

Meeting Abstract. 2019


Preclinical antitumor efficacy of senescence-inducing chemotherapy combined with a nanoSenolytic.

Galiana I; (...); Orzáez M

Article. 10.1016/j.jconrel.2020.04.045. 2020

  • Open Access.

Real-Time In Vivo Detection of Cellular Senescence through the Controlled Release of the NIR Fluorescent Dye Nile Blue

Lozano-Torres, B; (...); Martinez-Manez, R

Article. 10.1002/anie.202004142. 2020

  • Open Access.

Targeted-lung delivery of dexamethasone using gated mesoporous silica nanoparticles. A new therapeutic approach for acute lung injury treatment.

García-Fernández A; (...); Martínez-Máñez R

Article. 10.1016/j.jconrel.2021.07.010. 2021


The chemistry of senescence

Lozono-Torres, B; (...); Sancenon, F

Review. 10.1038/s41570-019-0108-0. 2019


The past, present, and future of breast cancer models for nanomedicine development

Boix-Montesinos, P; (...); Vicent, MJ

Review. 10.1016/j.addr.2021.03.018. 2021


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