Red de Transtornos Adictivos

A multi-omic study for uncovering molecular mechanisms associated with hyperammonemia-induced cerebellar function impairment in rats

Tarazona, S; (...); Felipo, V

Article. 10.1007/s10565-020-09572-y. 2021

A Multiomics Study To Unravel the Effects of Developmental Exposure to Endosulfan in Rats: Molecular Explanation for Sex-Dependent Effects

Tarazona, S; (...); Llansola, M

Article. 10.1021/acschemneuro.9b00304. 2019

A NIR light-triggered drug delivery system using core-shell gold nanostars-mesoporous silica nanoparticles based on multiphoton absorption photo-dissociation of 2-nitrobenzyl PEG

Hernández-Montoto A; (...); Sancenón F

Article. 10.1039/c9cc04260a. 2019

A targeted polypeptide-based nanoconjugate as a nanotherapeutic for alcohol-induced neuroinflammation.

Cuesta, Carlos Manuel; (...); Guerri, Consuelo

Article. 10.1016/j.nano.2021.102376. 2021

Bax transmembrane domain interacts with prosurvival Bcl-2 proteins in biological membranes

Andreu-Fernandez, V; (...); Orzaez, M

Article. 10.1073/pnas.1612322114. 2017

Bicuculline Reduces Neuroinflammation in Hippocampus and Improves Spatial Learning and Anxiety in Hyperammonemic Rats. Role of Glutamate Receptors

Malaguarnera, M; (...); Felipo, V

Article. 10.3389/fphar.2019.00132. 2019

Blockade of nitric oxide signalling promotes resilience to the effects of social defeat stress on the conditioned rewarding properties of MDMA in mice

Garcia-Pardo, MP; (...); Aguilar, MA

Article. 10.1016/j.niox.2020.03.001. 2020

BOK-MCL1 transmembrane interactions: a challenging target for cancer therapy

Sancho, M, Orzaez, M

Editorial Material. 10.1080/23723556.2020.1859918. 2021

Cytochrome c speeds up caspase cascade activation by blocking 14-3-3 epsilon-dependent Apaf-1 inhibition

Elena-Real, CA; (...); Diaz-Moreno, I

Article. 10.1038/s41419-018-0408-1. 2018

Chronic hyperammonemia alters in opposite ways membrane expression of GluA1 and GluA2 AMPA receptor subunits in cerebellum. Molecular mechanisms involved

Cabrera-Pastor, A; (...); Felipo, V

Article. 10.1016/j.bbadis.2017.10.031. 2018

Chronic hyperammonemia induces peripheral inflammation that leads to cognitive impairment in rats: Reversed by anti-TNF-alpha treatment

Balzano, T; (...); Felipo, V

Article. 10.1016/j.jhep.2019.01.008. 2020

Deep sequencing and miRNA profiles in alcohol-induced neuroinflammation and the TLR4 response in mice cerebral cortex

Urena-Peralta, JR; (...); Guerri, C

Article. 10.1038/s41598-018-34277-y. 2018

Determination of selected neurotoxic insecticides in small amounts of animal tissue utilizing a newly constructed mini-extractor

Seifertova, M; (...); Kocan, A

Article. 10.1007/s00216-017-0533-1. 2017

Developmental Exposure to Pesticides Alters Motor Activity and Coordination in Rats: Sex Differences and Underlying Mechanisms

Gomez-Gimenez, B; (...); Llansola, M

Article. 10.1007/s12640-017-9823-9. 2018

Differences in the Association of BH3-Only Proteins to Biological Membranes

Andreu-Fernandez, V; (...); Mingarro, I

Meeting Abstract. 10.1016/j.bpj.2016.11.1135. 2017

Dinoponera quadriceps venom as a source of active agents against Staphylococcus aureus

Rocha, LQ; (...); Martins, AMC

Article. 10.1016/j.toxicon.2020.11.003. 2021

Endosulfan and Cypermethrin Pesticide Mixture Induces Synergistic or Antagonistic Effects on Developmental Exposed Rats Depending on the Analyzed Behavioral or Neurochemical End Points

Gomez-Gimenez, B; (...); Felipo, V

Article. 10.1021/acschemneuro.7b00364. 2018

EU-OPENSCREEN: A Novel Collaborative Approach to Facilitate Chemical Biology

Brennecke, P; (...); Gribbon, P

Article. 10.1177/2472555218816276. 2019

Gender differences in the inflammatory cytokine and chemokine profiles induced by binge ethanol drinking in adolescence

Pascual, M; (...); Guerri, C

Article. 10.1111/adb.12461. 2017

Gene-Directed Enzyme Prodrug Therapy by Dendrimer-Like Mesoporous Silica Nanoparticles against Tumor Cells

Candela-Noguera, V; (...); Martinez-Manez, R

Article. 10.3390/nano11051298. 2021

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Gold Nanostars Coated with Mesoporous Silica Are Effective and Nontoxic Photothermal Agents Capable of Gate Keeping and Laser Induced Drug Release

Hernández Montoto A; (...); Martínez-Máñez R

Article. 10.1021/acsami.8b08395. 2018

Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)

Klionsky, DJ; (...); Tong, CK

Review. 10.1080/15548627.2020.1797280. 2021

Hybrid Mesoporous Nanocarriers Act by Processing Logic Tasks: Toward the Design of Nanobots Capable of Reading Information from the Environment

Llopis-Lorente, A; (...); Martinez-Manez, R

Article. 10.1021/acsami.8b05920. 2018

Hyperammonemia alters the mismatch negativity in the auditory evoked potential by altering functional connectivity and neurotransmission

Garcia-Garcia, R; (...); Felipo, V

Article. 10.1111/jnc.14941. 2020

Identification and validation of uterine stimulant methylergometrine as a potential inhibitor of caspase-1 activation

Garcia-Lainez, G; (...); Orzaez, M

Article. 10.1007/s10495-017-1405-z. 2017

Identification of an ASC oligomerization inhibitor for the treatment of inflammatory diseases

Soriano-Teruel, PM; (...); Orzaez, M

Article. 10.1038/s41419-021-04420-1. 2021

Increasing extracellular cGMP in cerebellum in vivo reduces neuroinflammation, GABAergic tone and motor in-coordination in hyperammonemic rats

Cabrera-Pastor, A; (...); Felipo, V

Article. 10.1016/j.bbi.2017.12.013. 2018

Inhibition of gamma-Secretase Leads to an Increase in Presenilin-1

Sogorb-Esteve, A; (...); Saez-Valero, J

Article. 10.1007/s12035-017-0705-1. 2018

Janus Gold Nanostars-Mesoporous Silica Nanoparticles for NIR-Light-Triggered Drug Delivery

Hernández Montoto A; (...); Sancenón F

Article. 10.1002/chem.201900750. 2019

Lack of TLR4 modifies the miRNAs profile and attenuates inflammatory signaling pathways.

Ureña-Peralta JR; (...); Guerri C

Article. 10.1371/journal.pone.0237066. 2020

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Mcl-1 and Bok transmembrane domains: Unexpected players in the modulation of apoptosis.

Lucendo E; (...); Orzáez M

Article. 10.1073/pnas.2008885117. 2020

MUC1 aptamer-capped mesoporous silica nanoparticles for controlled drug delivery and radio-imaging applications

Pascual, L; (...); Sancenon, F

Article. 10.1016/j.nano.2017.08.006. 2017

MUC1 Aptamer-Capped Mesoporous Silica Nanoparticles for Navitoclax Resistance Overcoming in Triple-Negative Breast Cancer

Vivo-Llorca, G; (...); Martinez-Manez, R

Article. 10.1002/chem.202001579. 2020

Peripheral inflammation induces neuroinflammation that alters neurotransmission and cognitive and motor function in hepatic encephalopathy: Underlying mechanisms and therapeutic implications

Cabrera-Pastor A; (...); Felipo V

Review. 10.1111/apha.13270. 2019

Peripheral treatment with Infliximab prevents glial activation and neuroinflammation and restores cognitive and motor alterations in rats with chronic liver failure

Balzano, T; (...); Felipo, V

Meeting Abstract. 2017

Preclinical antitumor efficacy of senescence-inducing chemotherapy combined with a nanoSenolytic.

Galiana I; (...); Orzáez M

Article. 10.1016/j.jconrel.2020.04.045. 2020

Real-Time In Vivo Detection of Cellular Senescence through the Controlled Release of the NIR Fluorescent Dye Nile Blue

Lozano-Torres, B; (...); Martinez-Manez, R

Article. 10.1002/anie.202004142. 2020

Rifaximin improves neuroinflammation and neurotransmission in cerebellum and hippocampus of rats with mild liver damage

Ivaylova, G; (...); Felipo, V

Meeting Abstract. 2021

Rifaximin Prevents T-Lymphocytes and Macrophages Infiltration in Cerebellum and Restores Motor Incoordination in Rats with Mild Liver Damage

Balzano, T; (...); Felipo, V

Article. 10.3390/biomedicines9081002. 2021

Role of NMDA and AMPA glutamatergic receptors in the effects of social defeat on the rewarding properties of MDMA in mice

Garcia-Pardo MP; (...); Aguilar MA

Article. 10.1111/ejn.14190. 2019

Senolysis Reduces Senescence in Veins and Cancer Cell Migration

Estepa-Fernandez, A; (...); Martinez-Manez, R

Article. 10.1002/adtp.202100149. 2021

Sex-dependent effects of developmental exposure to different pesticides on spatial learning. The role of induced neuroinflammation in the hippocampus

Gomez-Gimenez, B; (...); Felipo, V

Article. 10.1016/j.fct.2016.11.028. 2017

Sildenafil reduces neuroinflammation in cerebellum, restores GABAergic tone, and improves motor in-coordination in rats with hepatic encephalopathy

Agusti, A; (...); Felipo, V

Article. 10.1111/cns.12688. 2017

Sildenafil Treatment Eliminates Pruritogenesis and Thermal Hyperalgesia in Rats with Portacaval Shunts

Belghiti, M; (...); Felipo, V

Article. 10.1007/s11064-016-1980-3. 2017

Sustained hyperammonemia induces TNF-a in glial cells and Purkinje neurons by activating the TNFR1-NF-kappa B pathway

Ortiz, YMA; (...); Felipo, V

Meeting Abstract. 2021

Sustained hyperammonemia induces TNF-a IN Purkinje neurons by activating the TNFR1-NF-kappa B pathway

Balzano, T; (...); Felipo, V

Article. 10.1186/s12974-020-01746-z. 2020

Targeted-lung delivery of dexamethasone using gated mesoporous silica nanoparticles. A new therapeutic approach for acute lung injury treatment.

García-Fernández A; (...); Martínez-Máñez R

Article. 10.1016/j.jconrel.2021.07.010. 2021

Targeting inflammasome by the inhibition of caspase-1 activity using capped mesoporous silica nanoparticles

Garcia-Fernandez, A; (...); Orzaez, M

Article. 10.1016/j.jconrel.2017.01.002. 2017

The chemistry of senescence

Lozono-Torres, B; (...); Sancenon, F

Review. 10.1038/s41570-019-0108-0. 2019

The Dual Role of the GABA(A) Receptor in Peripheral Inflammation and Neuroinflammation: A Study in Hyperammonemic Rats

Malaguarnera, M; (...); Felipo, V

Article. 10.3390/ijms22136772. 2021

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The past, present, and future of breast cancer models for nanomedicine development

Boix-Montesinos, P; (...); Vicent, MJ

Review. 10.1016/j.addr.2021.03.018. 2021

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TLR4 Deficiency Affects the Microbiome and Reduces Intestinal Dysfunctions and Inflammation in Chronic Alcohol-Fed Mice

Cuesta, CM; (...); Guerri, C

Article. 10.3390/ijms222312830. 2021

Toll-like receptors 2 and 4 differentially regulate the self-renewal and differentiation of spinal cord neural precursor cells.

Sanchez-Petidier M, Guerri C, Moreno-Manzano V

Article. 10.1186/s13287-022-02798-z. 2022

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Treatment with anti-TNFa reduces neuroinflammation and restores neurotransmission, learning and motor coordination in rats with hepatic encephalopathy

Dadsetan, S; (...); Felipo, V

Meeting Abstract. 10.1016/S0168-8278(17)31589-1. 2017

Understanding MCL1: from cellular function and regulation to pharmacological inhibition

Sancho, M; (...); Orzaez, M

Review. 10.1111/febs.16136. 2022

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Unveiling Sex-Based Differences in the Effects of Alcohol Abuse: A Comprehensive Functional Meta-Analysis of Transcriptomic Studies.

Casanova Ferrer F; (...); García-García F

Article. 10.3390/genes11091106. 2020

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